An ongoing PubMed database research has found that cannabis, curcumin, vitamin D, and GABA improve 50 biomarkers that have been implicated in severe COVID-19 cases. The review found that all these biomarkers are made worse by glucose but can be improved by these four naturally occurring compounds. However, further clinical trials would be needed to validate preliminary findings and allow physicians to recommend this type of “safe, natural, and inexpensive” treatment.
The PubMed database reviews focused on the keywords CBD, THC, cannabis, curcumin, vitamin D, GABA (γ-Aminobutyric Acid), and glucose and covered both in-vivo and in-vitro studies.
From the research, it appears that a combination of cannabis derived CBD, curcumin (active ingredient in turmeric), vitamin D, and gamma-aminobutyric acid (found in green and black tea) can lower the concentration of substances that are increased in severe COVID-19 cases. At the same time, the research found that reducing sugar intake could improve symptoms in severe COVID-19 infection.
The researchers noted that previously clinical trials have been conducted on drugs that have shown positive markers in less than a dozen of COVID-19 biomarkers. Hence, they went further to propose that 54 biomarkers is indeed sufficient evidence to warrant clinical trials on the combined strategy of the four naturally occurring substances. This database review is ongoing.