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Is CBD For Diabetes Any Good?



Many patients with diabetes are turning to cannabidiol (CBD), and for varied reasons. Diabetes is a leading cause of disability and death across the globe. Chronic diabetes is associated with blindness, lower limb amputation, kidney failure, and heart attacks among others.

Diabetes affects about 32 million Americans and about 422 million people globally. By 2019, it was the ninth leading cause of death globally, directly causing about 1.5 million deaths.

Diabetes, which is a chronic condition is linked to insulin; lack of production, or loss of sensitivity of insulin. To date, there is no known cure for diabetes. Patients are usually offered supplemental insulin or managed by drugs that control blood sugar levels. However, some sources claim that diet-assisted diabetes reversal is possible.

The non-psychoactive cannabinoid was first isolated in 1940 is proving to be helpful in managing several conditions, among them is diabetes. Like other phytocannabinoids, CBD’s effects are linked to the dynamic endocannabinoid system (ECS).

The ECS is one of the vital systems that make up the human body, even though not much has been published about it. It is made up of endocannabinoids (they have similarities with the exogenous phytocannabinoids that are present in cannabis), endocannabinoid receptors, and enzymes.

Phytocannabinoids interact with the endocannabinoid receptors in the ECS and in this way they support vital functions in the body. This includes metabolism, hormonal function, appetite, memory and learning, pain and inflammation, and moods, and sleep among others.

CBD appears to have a weak binding affinity for both receptors of the ECS (CB1 &CB2). It appears to work through other mechanisms and pathways that are under investigation.

How Does CBD Treat Diabetes?

95% of those who suffer from diabetes have type 2 which means that they lack insulin sensitivity. Studies have linked this type of diabetes to chronic inflammation.

CBD Has Potent Anti-inflammatory Properties

CBD appears to have strong anti-inflammatory properties that may help with type 2 diabetes. A 2007 study investigated the effect of CBD in diabetes control.

The study was titled “cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption” is one that is of interest in diabetes control. This was a lab study involving non-obese diabetic mice. The researchers found that CBD exerts positive effects on several inflammation markers. Could this effect mitigate against the progression of chronic inflammation that happens in diabetes?

These researchers found that the non-obese mice that were treated with CBD had a lower risk of developing diabetes. At the same time, a 2016 study that was published in Diabetic Care did not support the anti-diabetic effects of CBD. The researchers found that CBD had little effectiveness’ on HDL cholesterol levels as well as other markers of diabetes such as insulin sensitivity. It would be insightful to know what kind of effects will be observed from large randomized clinical studies.


Lydia K. (Bsc. RN) is a cannabis writer, which, considering where you’re reading this, makes perfect sense. Currently, she is a regular writer for Mace Media. In the past, she has written for MyBud, RX Leaf & Dine Magazine (Canada), CBDShopy (UK) and Cannavalate & Pharmadiol (Australia). She is best known for writing epic news articles and medical pieces. Occasionally, she deviates from news and science and creates humorous articles. And boy doesn't she love that! She equally enjoys ice cream, as should all right-thinking people.