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Innovative Extraction Technique Yields Elevated Cannabinoid Levels with Enhanced Stability

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Cannabis extraction methods have long been an essential aspect of unlocking the plant's therapeutic potential. With advancements in technology and understanding, new methods emerge, each offering unique benefits and challenges. Among these innovators stands Peter Vermeul, whose accidental discovery has sparked curiosity and raised eyebrows in the cannabis community.

Vermeul's journey started more than four years ago when he developed his first CBG varieties. What followed were astonishing laboratory results that defied conventional wisdom. An extraction process that should have yielded a ratio of (at most) 10 of plant to extract instead yielded a substantially higher concentration of cannabinoids. For example, a CBG plant with 12% CBGa and 0.5% CBDa is converted into an extract with 15% CBGa and 17% CBDa. Such an anomaly led Vermeul to delve deeper into the extraction process, leading to a revelation that challenged existing norms.

Remarkable CBDa Stability Even After Many Years

Further research revealed not only the unusual outcome of the CBG extraction, but also the remarkable stability of CBDa in Vermeul's extracts. Typically, CBDa undergoes decarboxylation to CBD after maximum of 12 weeks. However, Vermeul's extracts retained their CBDa content even after many years, which baffled experts and defied scientific expectations.
The implications of Vermeul's discovery are profound. It suggests the existence of a new extraction method that can preserve not only CBDa, but also many other components present in the cannabis plant, including cannabinoid acids, terpenes and flavonoids. Such stability and retention of diverse compounds could revolutionize the cannabis industry, bringing improved therapeutic efficacy and broader applications for both medical and recreational users.

In Vermeul's Words

“The extraction method holds paramount importance; however, conventional methods such as alcohol or CO2 extraction often fail to retain the stable composition of CBDa extract alongside nearly all terpenes, flavonoids, cannabinoid acids, and other essential components found in the plant. In 2016, I stumbled upon a unique extraction technique that preserves the plant's composition in its original state, unaffected and unchanged. Even after years, I possess over eight distinct extracts from 2016, totaling more than 30 kg, each accompanied by its respective Certificate of Analysis (CoA) and repeatedly tested for consistency.
Notably, every strain boasts its unique composition of components, translating to individualized medicinal effects. This phenomenon is evident in patients' responses, as some respond solely to a specific strain while showing no reaction to others, despite similar THC and CBD ratios. Intriguingly, the stability of CBDa in my extracts remains unexplained by experts, and despite claims, no manufacturer has replicated this feat. Upon inquiry for CoAs verifying this stability, they often fall short, unable to provide secondary tests after six months, when CBDa conversion to CBD is significant.”

Vermeul's findings have attracted the attention of prominent figures in the field, including specialists like Dr. Raphael Mechoulam (R.I.P) from Israel and Vangelis Mitsis from Greece, while Vermeul shared his results with them. To date, no one has been able to fully explain the mechanisms behind Vermeul's unique extraction process.


Highlighting how extraction methods might alter the chemical profile of a given chemovar opens doors to understanding the nuanced effects of different cannabis formulations on therapeutic outcomes. It is conceivable that variations in extraction techniques could lead to differential concentrations of cannabinoids, terpenes, and other phytochemicals present in the plant. For instance, employing methods that prioritize the preservation of delicate compounds such as CBDa or specific terpenes could result in formulations with enhanced therapeutic properties tailored to address specific medical conditions. By selectively extracting and formulating cannabinoids and terpenes, it is plausible that these refined formulations could offer heightened efficacy in targeted treatment regimens, offering patients more precise and effective therapeutic interventions.



Lydia K. (Bsc. RN) is a cannabis writer, which, considering where you’re reading this, makes perfect sense. Currently, she is a regular writer for Mace Media. In the past, she has written for MyBud, RX Leaf & Dine Magazine (Canada), CBDShopy (UK) and Cannavalate & Pharmadiol (Australia). She is best known for writing epic news articles and medical pieces. Occasionally, she deviates from news and science and creates humorous articles. And boy doesn't she love that! She equally enjoys ice cream, as should all right-thinking people.