Alabama’s Second Medical Cannabis Dispensary Opens in Talladega

Alabama’s second medical cannabis dispensary is set to open Friday, August 28, 2026, in Talladega, according to the Alabama Medical Cannabis Commission. The new location is a second storefront for Callie’s Apothecary, the company that opened the state’s first medical cannabis dispensary in Montgomery on June 4, 2026.

The commission’s dispensary opening announcements list the Talladega store at 309 Battle Street W, Talladega, AL 35160, with hours of Monday through Friday, 10 a.m. to 6 p.m. The first Callie’s Apothecary location, at 5232 Atlanta Highway in Montgomery, keeps the same weekday hours.

Callie’s Apothecary confirmed the opening on its website, stating that the Talladega dispensary opens Friday, August 28, from 10 a.m. to 6 p.m. at 309 W Battle St. The company describes itself as an Alabama-licensed medical cannabis store serving registered patients, and states that it operates as a medical-only dispensary in compliance with Alabama law, with recreational sales not permitted.

The company said patients in and around Talladega can obtain the guidance and medical cannabis support offered at its Montgomery store “without making the drive to Montgomery.”

Entry Requirements and Patient Registration

Only registered patients and caregivers with a valid Alabama medical cannabis card are permitted to enter a dispensary, according to the commission. Callie’s Apothecary states that visitors must bring a valid government-issued photo ID and an Alabama medical cannabis card or proof of registration, and that both are required for entry and service. Appointments are not required, the company states.

To receive a medical cannabis card, the commission states that a person must be an Alabama resident, be at least 19 years of age or have a parent or legal guardian serve as a registered caregiver, have a qualifying medical condition, receive a recommendation from an Alabama physician certified by the Alabama Board of Medical Examiners to make medical cannabis recommendations, and be registered on the commission’s patient registry system.

The commission lists the following as qualifying conditions for medical cannabis treatment: autism spectrum disorder; cancer-related cachexia, nausea or vomiting, weight loss, or chronic pain; Crohn’s disease; depression; epilepsy or a condition causing seizures; HIV/AIDS-related nausea or weight loss; panic disorder; Parkinson’s disease; persistent nausea that is not significantly responsive to traditional treatment, with stated exceptions; post-traumatic stress disorder; sickle cell anemia; spasticity associated with a motor neuron disease, including amyotrophic lateral sclerosis; spasticity associated with multiple sclerosis or a spinal cord injury; a terminal illness; Tourette’s syndrome; and a condition causing chronic or intractable pain in which therapeutic intervention and opiate therapy is contraindicated or has proved ineffective.

Under the state’s medical cannabis statute, registered qualified patients aged 19 and older may purchase, possess, or use medical cannabis, while registered patients under 19 may use medical cannabis only with the assistance of a caregiver who is a parent or legal guardian. Patients and caregivers may not purchase more than 60 daily dosages and may not possess more than 70 daily dosages at any time.

Licensed Products and Planned Locations

Products permitted in Alabama include non-sugar-coated gelatinous cubes or cuboids, lozenges, tablets, capsules, tinctures, gels, oils, and creams for topical use, suppositories, transdermal patches, nebulizers, and liquids or oils for use in an inhaler, according to the commission. Prohibited products include raw plant material, products that could be smoked or vaped, and food products such as cookies or candies.

The statute, known as the Darren Wesley “Ato” Hall Compassion Act, was enacted as Act 2021-450. The commission is the state body charged with administering and enforcing the program, including licensing dispensaries and other medical cannabis facilities.

Based on dispensary licenses issued to date, the commission states that dispensing sites will be located in Athens, Attalla, Bessemer, Birmingham, Daphne, Mobile, Montgomery, Oxford, and Talladega. Callie’s Apothecary lists a third location at 1263 Greenmor Drive in Bessemer as coming soon.

The commission notes that one dispensary license it awarded on December 11, 2025, has been stayed, and that an additional three retail dispensing sites may be added with the issuance of an additional dispensary license. Administrative hearings are being conducted in the integrated facility license category, according to the commission. The commission may issue up to five integrated facility licenses, and each licensee may operate up to five dispensing sites, meaning up to 25 additional retail dispensing sites may be added with the issuance of those licenses.