MoreBetter Plans Mississippi Medical Cannabis Outcomes Registry

MoreBetter said in a November 10, 2026 announcement that it plans to build a statewide registry collecting patient-reported outcomes from Mississippi’s registered medical cannabis patients. Recruitment is expected to begin in the first quarter of 2027.

The program is intended to give the state and university research partners a continuous, patient-level view of how medical cannabis is used and how it relates to symptoms, prescription medication use and quality of life. MoreBetter would design the protocols, manage the study and participant interactions, collect the data and support analysis and publication with academic partners.

Kevin Provost, MoreBetter’s chief executive, said: “Every state with a medical cannabis market is asking the same questions about health outcomes and prescription use, and almost none of them have patient-level answers.”

What The Registry Would Measure

The registry is designed to track whether patients use fewer or more prescription medications over time; how pain, sleep, anxiety and overall well-being change; which products and patterns of use patients report; and what effects and unwanted effects they experience. It also aims to examine how those answers differ by condition.

Validated research instruments common to every participant are intended to combine responses into one statewide dataset. The protocols are designed for institutional review board review, with de-identification and data governance designed for regulated research. Selected aggregate, de-identified findings are intended for a public data portal that researchers, policymakers and the public could use.

MoreBetter describes the effort as a prospective observational research program and makes no claim that cannabis treats, prevents or cures any condition.

The company is also working with data partners to enable HIPAA-compliant linkage of patient-reported outcomes with electronic health record and claims data. Where available, that linkage would allow examination of hospital and clinic visits, out-of-pocket costs and the cost of care, including for state programs such as Medicaid.

Mississippi’s Patient Base and Next Steps

The Mississippi Medical Cannabis Program’s 2025 annual report counted 66,041 active patients as of December 15, 2025, compared with 49,626 as of December 30, 2024. Chronic pain and post-traumatic stress disorder were the two most commonly certified qualifying conditions in 2025.

MoreBetter said the statewide plan builds on an earlier study that enrolled about 300 Mississippi medical cannabis cardholders in 10 days. Recruitment for the new program is expected to be coordinated with Mississippi industry stakeholders, with participation details to be announced closer to launch.

MoreBetter describes the Mississippi effort as first-in-nation and the first in a planned series of statewide programs. The company expects more than a dozen additional states to follow, including Pennsylvania and Illinois.

The immediate milestone is patient recruitment, not the release of findings. The longer-term test is whether standardized patient responses, combined with any medical and claims records that become available, can give regulators and researchers useful statewide evidence on medication use, health outcomes and costs.