Delta 8 THC: Exploring The Science

When people think of THC, Delta 9 THC usually comes to mind—the most well-known psychoactive component of cannabis. However, Delta 9 isn’t the only form of THC worth discussing. Among the growing roster of THC analogues, Delta 8 THC has emerged as a rising star, earning nicknames like “decaf weed” or “diet weed” due to its milder effects. Delta 8 is relatively new to mainstream markets, and many are curious about its unique benefits and uses. Let’s take a closer look at what Delta 8 THC is and why it’s creating so much buzz.

What is Delta 8 THC?

Delta 8 THC is a naturally occurring cannabinoid found in cannabis and hemp plants, though in much smaller concentrations than its more famous cousin, Delta 9 THC. It has been gaining popularity because of its unique effects and therapeutic potential. Through selective breeding and advanced extraction methods, cultivators have found ways to produce higher concentrations of Delta 8, making it more accessible in products like tinctures, smokables, and edibles.

Chemically, Delta 8 THC is quite similar to Delta 9 THC but differs slightly in molecular structure, leading to noticeably different effects. Delta 8 does produce a psychoactive “high,” but many users describe it as less intense and more functional than what you’d experience with Delta 9.

What are the Benefits of Delta 8 THC?

Though it has only recently gained traction in the wellness community, scientific research into Delta 8 THC dates back several decades. Researchers are excited about its wide-ranging potential to support both physical and mental health. Here are some of the key benefits that Delta 8 THC could offer:

Eases Nausea

In a study conducted in 1995, Delta 8 THC showed great promise as a powerful anti-nausea treatment in a study¹ involving children undergoing chemotherapy. Researchers followed 8 children with cancer over the period of 2 years and a total of 480 combined chemotherapy treatments. Remarkably, not a single participant experienced vomiting during the trial. Many have taken notice of Delta-8 THC’s superior anti-nausea effects, and a US patent has been filed for the use of Delta 8 along with CBD for use as an anti-nausea, citing Delta 8 was 200% more effective than Delta 9 THC for this therapeutic use. These successes, paired with Delta 8’s milder psychoactive properties, make it an appealing option for those seeking relief from nausea without overwhelming side effects.

Appetite Booster

Interestingly, Delta 8 THC may actually be a better appetite stimulant² than Delta 9 THC. In animal studies, Delta 8 significantly increased food intake, suggesting it could be a helpful aid for individuals dealing with appetite loss.

Anxiety Relief

For many, Delta 8 THC offers a way to enjoy the benefits of THC without the heightened anxiety often associated with Delta 9. Delta 8 can help to calm nerves and alleviate stress while still allowing for mental clarity and focus.

Supporting Digestive Health

Delta 8 THC may also aid in digestive health, particularly for those suffering from conditions like irritable bowel syndrome (IBS). Its interaction with CB1 receptors helps support the gastrointestinal tract, providing relief from discomfort.

Pain and Inflammation Relief

Emerging research³ suggests that Delta 8 THC could also play a role in managing pain. Studies in animals have shown that it alleviates both acute and chronic pain, as well as inflammation. These findings provide a strong foundation for future clinical trials in humans.

Neuroprotectant

Delta 8 THC has also garnered attention for its neuroprotective qualities⁴. It promotes the production of acetylcholine, a neurotransmitter responsible for learning, memory, and overall cognitive function. This property could prove useful in treating neurological disorders such as Alzheimer’s and Parkinson’s, where cognitive decline is a major concern.

Anti-Cancer Properties

Decades ago, the U.S. government initiated research to determine whether Delta 8 THC harmed the immune system. While studying rats with lung cancer, scientists made an unexpected discovery—Delta 8 not only failed to damage the immune system but also reduced the size of tumors in the animals. Furthermore, the National Cancer Institute’s drug dictionary acknowledges Delta 8 THC as a potential therapeutic to relieve nausea, anxiety, and pain, as well as act as an appetite stimulant and neuroprotectant. With millions affected annually by cancer, it is prominent research continues on this critical subject.

Legal Status: Is Delta 8 THC Legal?

As of now, Delta 8 THC occupies a somewhat gray area in terms of legality. Thanks to the 2018 Farm Bill, cannabinoids derived from hemp are federally legal, provided they contain less than 0.3% Delta 9 THC. Since Delta 8 is typically derived from hemp, it technically fits within this legal framework. However, laws can vary by state, and some have opted to restrict or ban the sale of Delta 8 products. Always check local regulations before purchasing or using Delta 8 THC.

The Future of Delta 8 THC

Delta 8 THC has the potential to make a significant impact in the health and wellness sector. Its vast number of therapeutic properties have the potential to not only support daily health and wellness but also help individuals with debilitating illnesses. Research suggests that Delta 8 THC may be useful in managing a variety of more complex conditions, from neurodegenerative diseases like Alzheimer’s and Parkinson’s to cancer and chronic pain syndromes.

As scientists continue to uncover more about this remarkable cannabinoid, its potential role in supporting both disease management and overall health becomes clearer. Delta 8 THC could one day be a key tool in maintaining wellness while offering targeted relief for a wide range of ailments.

Study Reference:

^{1. Abrahamov, A., & Mechoulam, R. (1995). An efficient new cannabinoid antiemetic in pediatric oncology. Life Sciences, 56(23–24), 2097–2102. https://doi.org/10.1016/0024-3205(95)00194-b}

^{2. Avraham, Y., Ben-Shushan, D., Breuer, A., Zolotarev, O., Okon, A., Fink, N., Katz, V., & Berry, E. M. (2004). Very low doses of delta-8-THC increase food consumption and alter neurotransmitter levels following weight loss. Pharmacology Biochemistry and Behavior, 77(4), 675–684. https://doi.org/10.1016/j.pbb.2004.01.015}

^{3. Tagen, M., & Klumpers, L. E. (2022). Review of delta-8-tetrahydrocannabinol (Δ^8^-THC): Comparative pharmacology with Δ^9^-THC. British Journal of Pharmacology, 179(15), 3915–3933. https://doi.org/10.1111/bph.15865}

^{4. Tripathi, H. L., Vocci, F. J., Brase, D. A., & Dewey, W. L. (1987). Effects of cannabinoids on levels of acetylcholine and choline and on turnover rate of acetylcholine in various regions of the mouse brain. Alcohol and Drug Research, 7(5–6), 525–532. PMID: 3620017.}