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How Does CBD Treat Alcohol Use Disorder?

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A study has found that CBD shows promise in treating Alcohol Use Disorder by modulating brain activity and neurotransmitter systems. This exciting discovery opens new doors for potential treatments in addressing AUD.

Alcohol use disorder (AUD) poses significant challenges worldwide, yet effective treatments remain limited. Recent attention has turned to cannabidiol (CBD) as a potential therapeutic agent for managing AUD. However, the precise neurobiological mechanisms underlying CBD's effects on AUD are not fully understood.

This article highlights a systematic review of studies exploring how CBD influences the brain in healthy individuals. The goal being to uncover the intricate neurobiological pathways that may explain how CBD could alleviate the challenges of AUD.

Following the guidelines of the PRISMA framework, researchers meticulously combed through published studies on CBD and neuroimaging. By searching through peer-reviewed journals, they identified original clinical research shedding light on CBD's effects on brain function.

Among the multitude of studies, 16 met the criteria for inclusion in the review. These studies revealed intriguing insights into how CBD interacts with key neurotransmitters like γ-Aminobutyric acid (GABA) and glutamate in specific brain regions. Notably, CBD seems to tweak the workings of areas such as the basal ganglia and dorsal-medial prefrontal cortex. Additionally, CBD influences brain activity in regions linked to reward pathways, emotion regulation, and executive functioning.


From the findings, it appears that CBD holds promise as a potential tool in the arsenal against AUD. By modulating neurotransmitter systems and activity in crucial brain regions, CBD may offer a new approach to managing AUD symptoms. However, more research is needed to fully grasp how CBD works and to validate its effectiveness in treating AUD.

In essence, CBD emerges as an intriguing candidate for addressing the complex challenges of AUD, providing hope for individuals seeking effective solutions to this widespread problem.


Lydia K. (Bsc. RN) is a cannabis writer, which, considering where you’re reading this, makes perfect sense. Currently, she is a regular writer for Mace Media. In the past, she has written for MyBud, RX Leaf & Dine Magazine (Canada), CBDShopy (UK) and Cannavalate & Pharmadiol (Australia). She is best known for writing epic news articles and medical pieces. Occasionally, she deviates from news and science and creates humorous articles. And boy doesn't she love that! She equally enjoys ice cream, as should all right-thinking people.